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Category:ToxicologyQ:
Creating a link inside an iframe
I'm creating a page that needs to run a JavaScript iframe within it. However, it needs to have a link to another page that is within the same domain, and have it run a JavaScript function to hide or show content.
What's the best way to make this happen?
A:
You can't use JavaScript to open up an iframe from within a different domain, because the Javascript from that page would be running on another domain than your own.
If you need to use JavaScript to control the child frame, you'll need to open a child window from your frame.
IRF4 is required for the differentiation of TLR7-expressing DCs.
Dendritic cells (DCs) are essential for the initiation of adaptive immunity. Although DCs have been found to express Toll-like receptors (TLRs), it is unclear whether DCs are equipped with the ability to respond to TLR ligands. In this study, we show that TLR7 ligand induces the maturation and differentiation of bone marrow-derived DCs (BMDCs) and that the differentiation of BMDCs into Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) or MyD88-dependent TLR7-expressing DCs is MyD88-dependent but TRIF-independent. Furthermore, gene knockdown experiments demonstrated that the function of TRIF is mediated by transcriptional factor interferon regulatory factor 4 (IRF4). The data demonstrate that IRF4 plays a crucial role in the regulation of DC differentiation and function.A physiological model of electrical stimulation of peripheral nerve.
Peripheral nerve stimulation (PNS) provides a therapeutic option to restore functionality after a severe nerve injury. If its therapeutic benefits are to be determined, the physiological consequences of stimulation need to be understood. In this study, we develop a computational model that describes the electrical interaction between the stimulation electrode and the underlying nerve. This model was integrated with a previously published model of peripheral nerve anatomy and physiology, where the membrane properties and ion channels that govern the electrical conduction of nerve fibers were described. Using the model, we simulated the effects of a typical stimulation protocol on the rate of nerve conduction and the electrochemical dynamics that occur at the sites of stimulation. Our model predicts that for a 3 ms stimulus ac619d1d87
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